CMIT/MIT mixture comprises 5-chloro-2-methyl-4-thiazoline-3-ketone (CMIT) and 2-methyl-4-thiazoline-3-ketone (MIT). The bactericidal effect of CMIT/MIT is carried out by breaking the bond between bacteria and algae protein.

When contact with microbes, it can quickly inhibit their growth, thus leading to the death of these microbes. CMIT/MIT biocide has strong inhibition and biocidal effects on common bacteria, fungi, and alga.

CMIT/MIT has many advantages, such as high biocidal efficiency, good degradation, no residual, safety in operation, good compatibleness, good stabilization, and low cost in operation.

CMIT/MIT can mix with chlorine and most cation, anion, and non-ionic surfactants. When used at a high dosage, its bio sludge stripping effect is excellent.

CMIT/MIT is a kind of fungicidal with properties of broad-spectrum, high efficiency, low toxicity, and non-oxidative. It is the ideal biocidal in industrial circulating cool water systems and in wastewater treatment in the oilfield, papermaking, pesticide, cutting oil, leather, detergent, cosmetics, etc.

CAS No.:


Molecular Weight:


Structure Formula:

CMIT/MIT Structure Formula


Grade IGrade II
AppearanceAmber transparent liquidLight yellow or light green transparent liquid
Active content, %14.0 Min.1.50 Min.
 pH Value (as it)1.0~4.0 2.0~5.0
Density (20℃), g/cm31.25 Min.1.02 Min.
CMIT/MIT (wt %) 2.5~4.02.5~4.0
Notes: 2%, 4%, and 8% or any concentration can be supplied on demands.

Sterilization mechanism:

CMIT/MIT forms hydrogen bonds with alkaline groups on DNA molecules in proteins of bacteria through the active part of the heterocyclic ring. And adsorbed on the cells of the bacteria. This acts as an attack on the core of the cell. This destroys the structure of the DNA inside the cell and causes the cell to die.


When used as a sludge stripper for grade II of CMIT/MIT, 150-300 mg/L is preferred. When used as biocides, 80~100 mg/L is preferred and charged every 3~7 days. It can not be used together with oxidative fungicidal, such as chlorine. And not used in cooling water systems containing sulfur. When used together with the quaternary amine, the effect will be better. When the CMIT/MIT is used as an industrial fungicide, 0.05%~0.4% is preferred.

CMIT/MIT can generally be compounded with formaldehyde, formaldehyde releaser, 1227 (BKC), BNP, DBNPA, BIT, MIT, MBIT, MBT, TCMTB, OIT, etc.

Packing and Storage:

25 kg in plastic barrel, or confirmed by clients. Storage for ten months in room shady and dry place.

25kg plastic barrel

Safety Protection:

The CMIT/MIT mixture is corrosive. People should avoid contact with the eyes and skin. Personnel should be equipped with protective glasses and rubber gloves.

In case of contact with the skin and eyes, rinse immediately with plenty of water. In case of skin contact, immediately remove contaminated clothing and shoes and rinse with plenty of water for at least 15 minutes. Apply urea acetate or burn ointment to the affected area and seek medical attention immediately.


Isothiazolinone fungicide products were born in the early 1970s. CMIT/MIT was widely used in industrial fungicides.

In the late 1980s, chemical companies were very enthusiastic about the research of isothiazolinones. With the development of new derivatives such as MIT and OIT, the excellent performance of these products in terms of bactericidal properties and scope of use was gradually recognized.


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